Hair Loss Treatments

What is total alopecia?
The total alopecia totalis or alopecia is a disease characterized by massive hair loss (90%) of the scalp. It affects patients in an acute form (hair loss within weeks) or a more slowly (hair loss can progress to two years). Patients typically do not recover the lost hair and the disease becomes chronic. The total alopecia can affect patients of both sexes and all ages. Patients suffering from alopecia totalis also have psychological effects (anxiety, sadness) which are particularly serious in children and women, as well as young people.

What is the estimated number of patients suffering from total hair loss?
At the time of allocating a number of cases of alopecia total number of patients with this disease was about 2.5 per 10,000 inhabitants of the European Union. But the report submitted by the Committee for Orphan Medicinal Products (COMP) states that the number of patients with alopecia totalis is 5 for every 10,000 inhabitants of the European Union. This is equivalent to a total of about 115,000 people.
What treatments are available against the total alopecia?
There are no satisfactory methods have been approved to treat alopecia totalis or alopecia totalis.
How medicine is expected to total alopecia combat?
Hair loss alopecia seen in total is believed to be caused by immune system cells characteristic of the body’s defense mechanism that attacks the hair follicles in error by the agency. The Diphenylcyclopropenone can act as a local irritant and sensitizing the area which shows the total alopecia, which is the same as causing an allergic reaction himself. Thus, it is thought that provokes an immune response and production of immune cells that oppose the action of autoreactive cells that prevent hair loss. Thus it is thought that to allow hair growth at the local level, can be a successful treatment. This assumption must be confirmed at the time of marketing authorization.

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